Nyxoah’s Genio® Therapy Receives Significant 2026 Medicare Reimbursement Increases Under Final CMS Rule

Nyxoah’s Genio® Therapy Receives Significant 2026 Medicare Reimbursement Increases Under Final CMS Rule

Assignment to New Technology APC 1580 is positive news for Nyxoah’s U.S. commercial rollout by strengthening hospital and ASC economics

Mont–Saint–Guibert, Belgium – November 26, 2025, 7:45 am CET / 1:45 am ET – Nyxoah SA (Euronext Brussels/Nasdaq: NYXH) (“Nyxoah” or the “Company”), a medical technology company that develops breakthrough treatment alternatives for Obstructive Sleep Apnea (OSA) through neuromodulation, today announced that the U.S. Centers for Medicare & Medicaid Services (CMS) has finalized its CY2026 Hospital Outpatient Prospective Payment System (HOPPS) and Ambulatory Surgery Center (ASC) Rule. Within the final rule, CMS assigned CPT Code 64568, the code used for all Genio hypoglossal nerve stimulation (HGNS) implants, to New Technology Ambulatory Payment Classification (APC) 1580.

Effective January 1, 2026, Hospital Outpatient Department (HOPD) reimbursement for CPT 64568 will increase to approximately $45,000, a 48% rise compared to 2025. In addition, Ambulatory Surgery Centers (ASC) facility reimbursement will increase to $42,373, reflecting a 58% increase compared to 2025.

These updates apply uniformly to all procedures billed under CPT 64568, including Genio®, and strengthen the economic foundation supporting therapy adoption across U.S. hospital outpatient departments and ambulatory surgical centers. With CMS’ decision, Genio® enters 2026 with a stronger reimbursement framework that is expected to support broader adoption, increased procedural throughput, and expansion across Medicare–heavy institutions.

Genio®’s single–incision procedure is well suited for the ASC environment, and the significant increase in ASC facility payment creates new opportunities for therapy expansion and site–of–service diversification.

“CMS’ decision to significantly increase reimbursement for CPT 64568 reinforces the growing recognition of hypoglossal nerve stimulation as a high–value therapy for obstructive sleep apnea,” commented Olivier Taelman, Nyxoah's Chief Executive Officer.“ The new rates create a more favorable environment for expanding access to our Genio therapy across both outpatient hospitals and ASCs.”

About Nyxoah

Nyxoah is a medical technology company focused on the development and commercialization of innovative solutions to treat OSA. Nyxoah’s lead solution is the Genio system, a patient–centered, leadless and battery–free hypoglossal neurostimulation therapy for OSA, the world’s most common sleep disordered breathing condition that is associated with increased mortality risk and cardiovascular comorbidities. Nyxoah is driven by the vision that OSA patients should enjoy restful nights and feel enabled to live their life to its fullest.

Following the successful completion of the BLAST OSA study, the Genio system received its European CE Mark in 2019. Nyxoah completed two successful IPOs: on Euronext Brussels in September 2020 and NASDAQ in July 2021. Following the positive outcomes of the BETTER SLEEP study, Nyxoah received CE mark approval for the expansion of its therapeutic indications to Complete Concentric Collapse (CCC) patients, currently contraindicated in competitors’ therapy. Additionally, the Company announced positive outcomes from the DREAM IDE pivotal study and receipt of approval from the FDA for a subset of adult patients with moderate to severe OSA with an AHI of greater than or equal to 15 and less than or equal to 65.

For more information, please visit http://www.nyxoah.com/.

Caution – CE marked since 2019. FDA approved in August 2025 as prescription–only device.

Forward–looking statements

Certain statements, beliefs and opinions in this press release are forward–looking, which reflect the Company’s or, as appropriate, the Company directors’ or managements’ current expectations regarding the Genio system; the potential advantages of the Genio system; Nyxoah’s goals with respect to the potential use of the Genio system; the Company's commercialization strategy and entrance to the U.S. market; and the Company's results of operations, financial condition, liquidity, performance, prospects, growth and strategies. By their nature, forward–looking statements involve a number of risks, uncertainties, assumptions and other factors that could cause actual results or events to differ materially from those expressed or implied by the forward–looking statements. These risks, uncertainties, assumptions and factors could adversely affect the outcome and financial effects of the plans and events described herein. These risks and uncertainties include, but are not limited to, the risks and uncertainties set forth in the “Risk Factors” section of the Company’s Annual Report on Form 20–F for the year ended December 31, 2024, filed with the Securities and Exchange Commission (“SEC”) on March 20, 2025 and subsequent reports that the Company files with the SEC. A multitude of factors including, but not limited to, changes in demand, competition and technology, can cause actual events, performance or results to differ significantly from any anticipated development. Forward–looking statements contained in this press release regarding past trends or activities are not guarantees of future performance and should not be taken as a representation that such trends or activities will continue in the future. In addition, even if actual results or developments are consistent with the forward–looking statements contained in this press release, those results or developments may not be indicative of results or developments in future periods. No representations and warranties are made as to the accuracy or fairness of such forward–looking statements. As a result, the Company expressly disclaims any obligation or undertaking to release any updates or revisions to any forward–looking statements in this press release as a result of any change in expectations or any change in events, conditions, assumptions or circumstances on which these forward– looking statements are based, except if specifically required to do so by law or regulation. Neither the Company nor its advisers or representatives nor any of its subsidiary undertakings or any such person's officers or employees guarantees that the assumptions underlying such forward–looking statements are free from errors nor does either accept any responsibility for the future accuracy of the forward–looking statements contained in this press release or the actual occurrence of the forecasted developments. You should not place undue reliance on forward–looking statements, which speak only as of the date of this press release.

Contacts:

Nyxoah
John Landry, CFO
[email protected]

Rémi Renard
Chief Investor Relations & Corporate Communication Officer
[email protected]

Attachment


GLOBENEWSWIRE (Distribution ID 1001141004)

La Thérapie Genio® de Nyxoah Bénéficie d'une Augmentation Significative du Remboursement Medicare en 2026 en Vertu de la Règle Finale du CMS

La Thérapie Genio® de Nyxoah Bénéficie d'une Augmentation Significative du Remboursement Medicare en 2026 en Vertu de la Règle Finale du CMS

L'attribution à l’APC “nouvelle technologie” 1580 donne un élan significatif au lancement commercial de Nyxoah aux États–Unis en renforçant la rentabilité des hôpitaux et des centres de chirurgie ambulatoire

Mont–Saint–Guibert, Belgique – 26 novembre 2025, 7h45 CET / 1h45 ET – Nyxoah SA (Euronext Bruxelles/Nasdaq : NYXH) (« Nyxoah » ou la « Société ») une société de technologie médicale spécialisée dans le développement et la commercialisation de solutions innovantes pour le traitement de l'Apnée Obstructive du Sommeil (« AOS ») par neuromodulation, a annoncé aujourd'hui que les Centres américains pour les services Medicare et Medicaid (Centers for Medicare & Medicaid Services – CMS) ont annoncé avoir finalisé leur règlement pour le système de paiement prospectif des soins hospitaliers ambulatoires (Hospital Outpatient Prospective Payment System – HOPPS) et les centres de chirurgie ambulatoire (Ambulatory Surgery Center – ASC) pour l'année civile 2026. Dans la règle finale, CMS a attribué le code CPT 64568, utilisé pour tous les implants de stimulation du nerf hypoglosse (HGNS) Genio, à la classification de paiement ambulatoire pour les nouvelles technologies (Ambulatory Payment Classification – APC) 1580.

À compter du 1er janvier 2026, le remboursement des services ambulatoires hospitaliers (HOPD) pour le code CPT 64568 passera à environ 45 000 dollars, soit une augmentation de 48 % par rapport à 2025. En outre, le remboursement des centres de chirurgie ambulatoire (ASC) passera à 42 373 dollars, soit une augmentation de 58 % par rapport à 2025.

Ces mises à jour s'appliquent de manière uniforme à toutes les procédures facturées sous le code CPT 64568, y compris Genio®, et renforcent les bases économiques qui soutiennent l'adoption de cette thérapie dans les services ambulatoires des hôpitaux et les centres chirurgicaux ambulatoires aux États–Unis. Grâce à la décision du CMS, Genio® aborde l'année 2026 avec un cadre de remboursement plus solide qui devrait favoriser une adoption plus large, une augmentation du nombre de procédures et une expansion dans les établissements fortement dépendants de Medicare.

La procédure à incision unique de Genio® est parfaitement adaptée à l'environnement des centres de chirurgie ambulatoire (ASC), et l'augmentation significative des paiements versés à ces centres crée de nouvelles opportunités pour l'expansion des traitements et la diversification des lieux de soins.

“La décision de CMS d'augmenter considérablement le remboursement pour le CPT 64568 renforce la reconnaissance croissante de la stimulation du nerf hypoglosse comme traitement de grande valeur pour l'apnée obstructive du sommeil,” a commenté Olivier Taelman, Chief Executive Officer de Nyxoah.“ Les nouveaux tarifs créent un environnement plus favorable à l'élargissement de l'accès à notre traitement Genio dans les hôpitaux ambulatoires et les centres de chirurgie ambulatoire.”

À propos de Nyxoah
Nyxoah opère dans le secteur des technologies médicales. Elle se concentre sur le développement et la commercialisation de solutions innovantes destinées à traiter le Syndrome d’Apnées Obstructives du Sommeil (SAOS). La principale solution de Nyxoah est le système Genio®, une thérapie de neurostimulation du nerf hypoglosse sans sonde et sans batterie qui a reçu le marquage CE, centrée sur le patient et destinée à traiter le Syndrome d’Apnées Obstructives du Sommeil (SAOS), le trouble respiratoire du sommeil le plus courant au monde. Ce dernier est associé à un risque accru de mortalité et des comorbidités, dont les maladies cardiovasculaires. La visions de Nyxoah est que les patients souffrant de SAOS doivent pouvoir profiter de nuits réparatrices et vivre pleinement leur vie.

À la suite de la finalisation probante de l’étude BLAST OSA, le système Genio® a reçu le marquage européen CE en 2019. Nyxoah a réalisé avec succès deux IPO : l’une sur Euronext Bruxelles en septembre 2020 et l’autre sur le NASDAQ en juillet 2021. Grâce aux résultats positifs de l'étude BETTER SLEEP, Nyxoah a reçu le marquage CE pour l’extension de ses indications thérapeutiques aux patients souffrant de collapsus concentrique complet (CCC), pour lesquels les thérapies concurrentes sont actuellement contre–indiquées. En outre, la Société a annoncé les résultats positifs de l'étude pivot DREAM IDE et l'obtention de l'autorisation de la FDA pour un sous–groupe de patients adultes atteints d'AOS modérée à sévère avec un IAH supérieur ou égal à 15 et inférieur ou égal à 65.

Pour plus d’informations, visitez www.nyxoah.com

Attention – marquage CE depuis 2019. Approuvé par la FDA en août 2025 en tant que dispositif disponible uniquement sur prescription médicale.

DÉCLARATIONS PROSPECTIVES
Certaines déclarations, convictions et opinions contenues dans le présent communiqué de presse sont prospectives et reflètent les attentes actuelles de la Société ou, le cas échéant, de ses administrateurs ou de sa direction concernant concernant la clôture du placement privé, l'offre directe enregistrée et le financement par obligation convertible, le système Genio®; les études cliniques prévues et en cours sur le système Genio®; les avantages potentiels du système Genio®; les objectifs de Nyxoah en matière de développement, de parcours réglementaire et d'utilisation potentielle du système Genio® ; la stratégie de commercialisation de la Société et son entrée sur le marché américain ; et les résultats d'exploitation, la situation financière, la liquidité, les performances, les perspectives, la croissance et les stratégies de la Société. De par leur nature, les déclarations prospectives comportent un certain nombre de risques, d'incertitudes, d'hypothèses et d'autres facteurs qui pourraient faire en sorte que les résultats ou événements réels diffèrent sensiblement de ceux exprimés ou sous–entendus dans les déclarations prospectives. Ces risques, incertitudes, hypothèses et facteurs pourraient avoir une incidence défavorable sur les résultats et les effets financiers des plans et événements décrits dans le présent document. En outre, ces risques et incertitudes comprennent, sans s'y limiter, la satisfaction des conditions requises pour la clôture de chacun du placement privé, de l'offre directe enregistrée et du financement par obligation convertible, ainsi que la réalisation des clôtures respectives, les risques et incertitudes énoncés dans la section « Risk Factors » du Annual Report on Form 20–F de la Société pour l'exercice clos le 31 décembre 2024, déposé auprès de la Securities and Exchange Commission (« SEC ») le 20 mars 2025, et dans les rapports ultérieurs que la Société dépose auprès de la SEC. Une multitude de facteurs, y compris, mais sans s'y limiter, les changements dans la demande, la concurrence et la technologie, peuvent faire en sorte que les événements, les performances ou les résultats réels diffèrent considérablement de toute évolution prévue. Les déclarations prospectives contenues dans le présent communiqué de presse concernant les tendances ou les activités passées ne constituent pas des garanties de performances futures et ne doivent pas être considérées comme une indication que ces tendances ou activités se poursuivront à l'avenir. En outre, même si les résultats ou développements réels sont conformes aux déclarations prospectives contenues dans le présent communiqué de presse, ces résultats ou développements ne sont pas nécessairement indicatifs des résultats ou développements futurs. Aucune déclaration ni garantie n'est faite quant à l'exactitude ou à l'équité de ces déclarations prospectives. Par conséquent, la Société décline expressément toute obligation ou engagement de publier des mises à jour ou des révisions des déclarations prospectives contenues dans le présent communiqué de presse à la suite d'un changement dans les attentes ou d'un changement dans les événements, les conditions, les hypothèses ou les circonstances sur lesquels ces déclarations prospectives sont fondées, sauf si la loi ou la réglementation l'exige expressément. Ni la Société, ni ses conseillers ou représentants, ni aucune de ses filiales, ni aucun des dirigeants ou employés de ces personnes ne garantissent que les hypothèses sous–jacentes à ces déclarations prospectives sont exemptes d'erreurs, et n'acceptent aucune responsabilité quant à l'exactitude future des déclarations prospectives contenues dans le présent communiqué de presse ou à la réalisation effective des développements prévus. Vous ne devez pas vous fier indûment aux déclarations prospectives, qui ne sont valables qu'à la date du présent communiqué de presse.

Contacts :

Nyxoah
John Landry, CFO
[email protected]

Rémi Renard
Chief Investor Relations & Corporate Communication Officer
[email protected]

Pièce jointe


GLOBENEWSWIRE (Distribution ID 1001141004)

TTEC Expands Operations in Egypt Following Global Offshoring Summit Engagement

AUSTIN, Texas, Nov. 25, 2025 (GLOBE NEWSWIRE) — TTEC Holdings, Inc. (NASDAQ: TTEC), a leading global CX (customer experience) technology and services innovator for AI–enhanced CX, today announced a major expansion of its Egypt operations following the 2025 Global Offshoring Summit in Cairo.

During the visit, TTEC Engage President John Abou participated in a Presidential Roundtable with global industry leaders, met with senior Egyptian government leaders including the Prime Minister of Egypt and Minister of ICT, and signed a Memorandum of Understanding (MOU) with the Information Technology Industry Development Agency (ITIDA) to support the company’s plan to scale its Cairo operations. Under the agreement, TTEC will expand its workforce by an additional 3,500 employees by 2029 to meet growing global client demand.

Expanding a Strategic Global Hub

TTEC first entered Egypt in 2023 and expanded again in early 2025 with the opening of its state–of–the–art facility in Maadi Technology Park. The site currently has over 500 employees who can support 11 languages — Arabic, English, French, German, Italian, Spanish, Dutch, Portuguese, Russian, Turkish, and Hebrew — and the workforce will continue to scale as client needs grow.

“Egypt has become an essential part of our global delivery network,” said Abou. “The strength of Egypt’s multilingual talent, combined with the support we’ve received from ITIDA and the Egyptian government, positions Cairo as a world–class hub for delivering the future of customer experience.”

Accelerating Egypt’s Digital Services Growth

TTEC’s Cairo facility enhances the company’s ability to deliver integrated omnichannel support — including voice, chat, social media, messaging, analytics, and back–office services. It also serves as an innovation hub for piloting next–generation CX technologies and AI–enabled solutions for global clients.

The expansion will create thousands of jobs across frontline support, operations, technology, data analysis, and quality assurance, supported by extensive training in AI tools, cloud systems, cybersecurity, and multilingual engagement.

“TTEC’s continued investment reinforces Egypt’s position as a leading destination for global offshoring and digital services,” said Eng. Ahmed Elzaher, CEO of ITIDA. “We look forward to deepening our partnership as TTEC scales its presence in Cairo. At ITIDA, we view each new center and every expansion as a commitment — a commitment to help it grow and ensure it unlocks its full potential.”

About TTEC
TTEC (pronounced T–TEC) Holdings, Inc. (NASDAQ: TTEC) is a leading global CX (customer experience) technology and services innovator for AI–enabled digital CX solutions. Serving iconic and disruptive brands, TTEC’s outcome–based solutions span the entire enterprise, touch every virtual interaction channel, and improve each step of the customer journey. Leveraging next–gen digital technology, the Company's TTEC Digital business designs, builds, and operates omnichannel contact center technology, CRM, AI, and analytics solutions. The Company’s TTEC Engage business delivers AI–enhanced customer engagement, customer acquisition and growth, tech support, back office, and fraud prevention services. Founded in 1982, the Company's singular obsession with CX excellence has earned it leading client, customer, and employee satisfaction scores across the globe. The Company’s employees operate on six continents and bring technology and humanity together to deliver happy customers and differentiated business results. To learn more visit us at https://www.ttec.com/emea

Media Contact
Meredith Matthews
[email protected]

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/e6fdd6c3–2b1a–4dd2–99b4–49dc0d6db03c

A video accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/f7c73c85–1b74–494b–95a9–6941088122de


GLOBENEWSWIRE (Distribution ID 9592560)

Enlivex annonce un placement privé de 212 000 000 $ pour lancer la première stratégie au monde de trésorerie d’actifs numériques sur les marchés prédictifs, via l’accumulation de jetons RAIN, et la nomination de Matteo Renzi, ancien Premier ministre italien, à son conseil d’administration

– À la clôture du placement privé, Enlivex adoptera la première stratégie au monde de trésorerie d’actifs numériques sur les marchés prédictifs RAIN, via l’accumulation de jetons RAIN.

– RAIN est un protocole de prédiction et d’options entièrement décentralisé qui redéfinit les écosystèmes des marchés prédictifs et fournit une plateforme puissante pour la création de marchés on–chain, conçue pour la transparence, l’automatisation et la participation de la communauté.

– M. Matteo Renzi, ancien Premier ministre italien, sera nommé au conseil d’administration d’Enlivex après la clôture du placement privé.

– Enlivex poursuivra le développement clinique d’Allocetra™, un traitement potentiellement révolutionnaire contre l’arthrose du genou, un marché en pleine croissance avec des besoins médicaux importants non satisfaits.

– Le prix par action est de 1 $, ce qui représente une prime de 11,5 % par rapport au cours de clôture précédent.

NES–ZIONA, Israël, 25 nov. 2025 (GLOBE NEWSWIRE) — Enlivex Therapeutics Ltd. (Nasdaq : ENLV, « Enlivex » ou « la Société »), une société d’immunothérapie clinique spécialisée dans la reprogrammation des macrophages, annonce ce jour la conclusion d’un contrat d’achat de titres dans le cadre d’un placement privé (PIPE) portant sur l’achat et la vente de 212 000 000 actions ordinaires (ou d’équivalents d’actions ordinaires) à un prix de 1 $ par action, soit une prime de 11,5 % par rapport au cours de clôture du 21 novembre 2025. Le produit brut total attendu est d’environ 212 000 000 $ (financé en USD et en USDT), avant déduction des commissions de placement et autres frais (la « Transaction »). Enlivex a l’intention d’utiliser le produit net du PIPE pour mettre en œuvre la première stratégie de trésorerie de jetons RAIN sur les marchés prédictifs, tout en continuant à se concentrer sur les activités principales de la Société.

RAIN est un protocole de prédictions et d’options entièrement décentralisé, construit sur le réseau Arbitrum. Le protocole est entièrement exempt de permission, permettant à quiconque de créer et de négocier des options personnalisées sur n’importe quel marché. Les résultats du marché peuvent être déterminés par l’IA, et la plateforme est régie par le jeton RAIN, qui intègre un mécanisme déflationniste de rachat et de destruction. Conçu pour être l’« Uniswap » des marchés prédictifs, RAIN est un protocole où chacun, partout dans le monde, peut créer tout type de marché, public ou privé, dans n’importe quelle langue.

« Compte tenu de l’intérêt récent des institutions pour les principales sociétés de marchés prédictifs (investissement de 2 milliards de dollars de la société mère du NYSE dans Polymarket et tour de financement de 300 millions de dollars de Kalshi mené par Andreessen Horowitz (a16z) et Sequoia Capital), il semble que ce secteur arrive à maturité et présente un fort potentiel de croissance. Nous pensons qu’après la clôture de cette transaction et la mise en œuvre de la stratégie de trésorerie RAIN, Enlivex deviendra la première société cotée en bourse aux États–Unis à offrir aux investisseurs une exposition aux marchés prédictifs, l’un des secteurs les plus dynamiques de l’industrie cryptographique », a déclaré Shai Novik, président du conseil d’administration d’Enlivex. « Le protocole décentralisé de RAIN utilise la technologie blockchain pour permettre aux participants de négocier sur les anticipations d’événements futurs, et nous pensons qu’il deviendra une force dominante dans ce segment de marché en pleine expansion. »

Et M. Novik d’ajouter : « Parallèlement à la gestion du portefeuille de trésorerie RAIN, Enlivex poursuivra ses activités existantes axées sur le développement clinique avancé d’Allocetra™, un nouveau traitement conçu pour traiter l’arthrose, une maladie articulaire. L’arthrose est de loin la forme d’arthrite la plus courante, touchant plus de 32,5 millions d’Américains et plus de 300 millions d’individus à travers le monde. Je souhaite la bienvenue à M. Matteo Renzi au sein du conseil d’administration d’Enlivex et je me réjouis de travailler avec lui pour créer de la valeur pour les actionnaires d’Enlivex. »

La clôture de la transaction devrait avoir lieu au plus tard le 25 novembre 2025 (la « Clôture »), sous réserve du respect des conditions de clôture habituelles.

BTIG agit en tant qu’agent de placement unique et conseiller financier exclusif pour la transaction. Greenberg Traurig, P.A. et FISCHER (FBC & Co.) agissent en tant que conseillers juridiques d’Enlivex, tandis que DLA Piper et Gornitzky & Co. agissent en tant que conseillers juridiques de BTIG.

Le présent communiqué de presse ne constitue pas une offre de vente ni une sollicitation d’offre d’achat de titres et ne constitue pas une offre, une sollicitation ou une vente dans toute juridiction où une telle offre, sollicitation ou vente serait illégale.

À PROPOS D’ENLIVEX

Enlivex sera la première société cotée en bourse à développer une stratégie de trésorerie axée sur RAIN, qui deviendra l’actif principal de réserve de la Société. En adoptant cette nouvelle politique de trésorerie, Enlivex souhaite offrir aux investisseurs une exposition au RAIN et promouvoir son rôle en tant que capital numérique.

En outre, Enlivex mène des activités opérationnelles axées sur le développement clinique avancé d’Allocetra™, une thérapie novatrice destinée au traitement de l’arthrose. L’arthrose est de loin la forme d’arthrite la plus courante, touchant plus de 32,5 millions d’Américains et plus de 300 millions d’individus à travers le monde. Environ la moitié des genoux présentant des lésions du ligament croisé antérieur développent de l’arthrose dans les 5 à 15 ans. On estime que 78 millions d’Américains seront atteints d’arthrose d’ici à 2040. L’arthrose symptomatique du genou est particulièrement fréquente et invalidante : 40 % des hommes et 47 % des femmes en développeront au cours de leur vie. L’arthrose est à l’origine de plus d’un million d’hospitalisations par an aux États–Unis, principalement pour des prothèses articulaires totales. Le fardeau de l’arthrose est énorme, et le besoin de traitements qui réduisent la douleur et l’invalidité qui en découle pour les personnes atteintes d’arthrose est crucial. À la connaissance de la Société, il n’existe actuellement aucun médicament approuvé par la Food and Drug Administration (FDA) américaine ou l’Agence européenne des médicaments (EMA) qui ait démontré sa capacité à arrêter, ralentir ou inverser la progression des lésions structurelles de l’articulation.

Déclarations prospectives

Le présent communiqué de presse contient des déclarations prospectives au sens de l’article 27A de la loi américaine Securities Act (loi sur les valeurs mobilières) de 1933, dans sa version modifiée, et de l’article 21E de la loi américaine Securities Exchange Act (loi sur les Bourses de valeurs) de 1934, dans sa version modifiée. Ces déclarations prospectives peuvent être identifiées par des termes tels que « prévoit », « planifie », « projette », « va », « peut », « anticipe », « croit », « devrait », « pourrait », « entend », « estime », « suggère », « vise », « a le potentiel de », ainsi que par d’autres expressions de sens similaire, y compris des déclarations relatives aux avantages anticipés et au calendrier prévu pour l’achèvement de la Transaction proposée et des opérations qui y sont liées, à l’utilisation envisagée du produit de la Transaction, aux actifs qui seront détenus par la Société, au marché, au prix et à la liquidité futurs attendus des actifs numériques acquis par la Société, aux conditions macroéconomiques et politiques entourant les actifs numériques, au plan de création de valeur de la Société et à ses avantages stratégiques, à la taille du marché et aux opportunités de croissance, aux conditions réglementaires, à la position concurrentielle ainsi qu’à l’intérêt d’autres entreprises pour des stratégies similaires, aux tendances technologiques et de marché, à la situation financière et à la performance futures, et aux impacts financiers attendus de la Transaction proposée décrite dans le présent document. Chaque déclaration prospective figurant dans le présent communiqué est soumise à des risques et incertitudes susceptibles d’entraîner des résultats réels sensiblement différents de ceux exprimés ou sous–entendus par ces déclarations. Les risques et incertitudes applicables incluent, entre autres : le risque que la Transaction proposée ne soit pas finalisée dans les délais prévus, voire pas du tout ; l’échec à réaliser les avantages anticipés de la Transaction et de la stratégie de trésorerie en actifs numériques proposée ; les changements dans les conditions commerciales, de marché, financières, politiques et réglementaires ; les risques liés aux opérations et à l’activité de la Société, y compris la forte volatilité du prix du RAIN et d’autres cryptomonnaies ; le risque que le prix des actions ordinaires de la Société soit fortement corrélé au prix des actifs numériques qu’elle détient ; les risques liés à l’intensification de la concurrence dans les secteurs d’activité actuels et futurs de la Société ; les risques liés aux incertitudes juridiques, commerciales, réglementaires et techniques significatives concernant les actifs numériques de manière générale ; les risques liés au traitement fiscal des actifs numériques aux États–Unis et à l’étranger ; ainsi que les autres risques et incertitudes figurant dans les documents déposés par la Société auprès de la Securities and Exchange Commission. Les déclarations prospectives figurant dans ce communiqué ne s’expriment qu’à la date du présent document, et la Société décline toute obligation de les réviser ou de les mettre à jour, sauf si la loi applicable l’exige.

CONTACT ENLIVEX

Shachar Shlosberger, directeur financier
Enlivex Therapeutics, Ltd.
[email protected]

CONTACT RELATIONS INVESTISSEURS

KCSA Strategic Communications
Jack Perkins
[email protected]


GLOBENEWSWIRE (Distribution ID 9592217)

Enlivex Anuncia Colocação Privada de US $212.000.000 para Início da Primeira Estratégia de Previsão de Mercados de Tesouro de Ativos Digitais do Mundo, via Acumulação de tokens RAIN, e a Nomeação de Matteo Renzi, Ex-Primeiro-Ministro da Itália, para seu Conselho

– Após o fechamento da colocação privada, a Enlivex adotará a primeira estratégia de tesouro de ativos digitais de token de previsão RAIN do mundo, por meio do acúmulo de token RAIN.

– RAIN é um protocolo de previsões e opções totalmente descentralizado que redefine os ecossistemas preditivos de mercado e fornece uma potente plataforma para a criação de mercado on–chain – desenvolvida para transparência, automação e participação da comunidade.

– O Sr. Matteo Renzi, ex–primeiro–ministro da Itália, será nomeado para o Conselho Diretor da Enlivex após o encerramento da colocação privada.

– A Enlivex continuará o desenvolvimento clínico do Allocetra™, uma terapêutica potencialmente revolucionária para a osteoartrite do joelho, um mercado crescente com necessidades médicas significativas não atendidas.

– Preço por ação de US $1,00, representando um prêmio de 11,5% do preço do fechamento anterior.

NES–ZIONA, Israel, Nov. 25, 2025 (GLOBE NEWSWIRE) — A Enlivex Therapeutics Ltd. (Nasdaq: ENLV, “Enlivex” ou “a Empresa”), uma empresa de imunoterapia de reprogramação de macrófagos em estágio clínico, anunciou hoje que fechou um contrato de compra de valores mobiliários para um investimento privado em capital público (PIPE) para a compra e venda de 212.000.000 ações ordinárias (ou equivalentes de ações ordinárias em seu lugar) a um preço de US $ 1,00 por ação, representando um prêmio de 11,5% do preço de fechamento das ações em 21 de novembro de 2025, com receitas brutas agregadas previstas de aproximadamente US $212.000.000 (financiadas em uma combinação de $USD e USDT), antes da dedução das taxas do agente de colocação e outras despesas da oferta (a “Transação”). A Enlivex pretende usar os recursos líquidos do PIPE para implementar a primeira estratégia de tesouro de token dos mercados de previsão RAIN, enquanto continua seu foco nas principais operações da Empresa.

RAIN é um protocolo de previsões e opções totalmente descentralizado, criado na rede Arbitrum. O protocolo não exige permissão, viabilizando que qualquer pessoa crie e negocie opções personalizadas em qualquer mercado. Os resultados do mercado podem ser resolvidos por IA, e a plataforma é governada pelo token RAIN, que possui um mecanismo de Buyback & Burn deflacionário integrado. Projetado para ser o “Uniswap” dos mercados de previsão, RAIN é um protocolo onde qualquer pessoa, de qualquer lugar, pode criar qualquer tipo de mercado, seja público ou privado, em qualquer idioma.

“Com o recente interesse institucional em empresas líderes em mercados de previsão – investimento de US $2 bilhões da controladora da NYSE no Polymarket e a rodada de financiamento de US $300 milhões da Kalshi liderada ela Andreessen Horowitz (a16z) e Sequoia Capital – parece que este setor está amadurecendo e tem um forte potencial de crescimento. Acreditamos que, após o fechamento desta transação e a implementação da estratégia de tesouro RAIN, a Enlivex será a primeira empresa pública negociada nos EUA a fornecer aos investidores uma exposição aos mercados de previsão, um dos setores que mais crescem na indústria de criptomoedas”, disse Shai Novik, Presidente do Conselho de Administração da Enlivex. “O protocolo descentralizado RAIN usa a tecnologia blockchain para permitir que os participantes negociem com base nas expectativas de eventos futuros, e acreditamos que ele passará a ser uma força dominante neste segmento de mercado em expansão.”

O Sr. Novik acrescentou: “Além de gerenciar o portfólio de tesouro RAIN, a Enlivex continuará suas operações existentes focadas no desenvolvimento clínico em estágio avançado do Allocetra™, uma nova terapia projetada para tratar a osteoartrite da doença articular. A osteoartrite é de longe a forma mais comum de artrite, afetando mais de 32,5 milhões de americanos e mais de 300 milhões de pessoas em todo o mundo. Gostaria de dar as boas–vindas ao Sr. Matteo Renzi ao Conselho de Administração da Enlivex. Estou pronto para trabalhar em conjunto com o Sr. Renzi para criar valor para os acionistas da Enlivex.”

O fechamento da Transação deve ocorrer em ou por volta de 25 de novembro de 2025, mediante a satisfação das condições habituais de fechamento.

A BTIG está atuando como único agente de colocação e consultor financeiro exclusivo da Transação. Greenberg Traurig, P.A. e FISCHER (FBC & Co.) atuam como consultores jurídicos da Enlivex, e DLA Piper e Gornitzky & Co. atuam como consultores jurídicos da BTIG.

Este comunicado de imprensa não constitui uma oferta de venda nem uma solicitação de uma oferta de compra de quaisquer valores mobiliários, e não constitui uma oferta, solicitação ou venda em qualquer jurisdição em que tal oferta, solicitação ou venda seja ilegal.

SOBRE A ENLIVEX

A Enlivex será a primeira companhia de capital aberto a desenvolver uma estratégia de tesouro centrada no RAIN, que será o principal ativo de reserva de tesouro da Empresa. Ao adotar sua nova política de tesouro, a Enlivex pretende fornecer aos investidores exposição ao RAIN e defender seu papel como capital digital.

Além disso, a Enlivex tem um negócio operacional focado no desenvolvimento clínico em estágio avançado do Allocetra™, uma nova terapia projetada para tratar a osteoartrite da doença articular. A osteoartrite é de longe a forma mais comum de artrite, afetando mais de 32,5 milhões de americanos e mais de 300 milhões de pessoas em todo o mundo. Cerca de metade dos joelhos com lesões no LCA desenvolvem osteoartrite dentro de 5 a 15 anos. Estima–se que 78 milhões de americanos terão osteoartrite até o ano de 2040. A osteoartrite sintomática do joelho é particularmente prevalente e incapacitante, com 40% dos homens e 47% das mulheres desenvolvendo osteoartrite do joelho ao longo da vida. A osteoartrite é responsável por mais de um milhão de hospitalizações anuais nos Estados Unidos, principalmente para substituição total da articulação. O ônus da osteoartrite é enorme, e a necessidade de tratamentos para reduzir a dor e a incapacidade das pessoas com osteoartrite é essencial. Tanto quanto é do conhecimento da Empresa, atualmente não existem medicamentos aprovados pela Food and Drug Administration dos EUA (FDA) ou pela Agência Europeia de Medicamentos (EMA) que tenham demonstrado deter, retardar ou reverter a progressão dos danos estruturais na articulação.

Declarações de Previsão

Este comunicado contém “declarações de previsão” de acordo com a definição do termo estabelecido na Seção 27A da Lei de Valores Mobiliários (Securities Act) de 1933 e suas alterações, e na Seção 21E da Lei de Mercados Mobiliários (Securities Exchange Act) de 1934, e suas emendas. Essas declarações de previsão podem ser identificadas por palavras como “espera”, “planeja”, “projeta”, “irá”, “pode”, “antecipa”, “acredita”, “deveria”, “faria”, “poderia”, “pretende”, “estima”, “sugere”, “visa”, “tem o potencial de” e outras palavras de significado semelhante, incluindo declarações relacionadas aos benefícios antecipados e ao momento da conclusão da Transação proposta e afins, o uso pretendido dos recursos da Transação, os ativos a serem mantidos pela Empresa, o mercado futuro previsto, preço e liquidez dos ativos digitais que a Empresa adquire, as condições macro e políticas em torno dos ativos digitais, o plano da Empresa para criação de valor e vantagens estratégicas, tamanho do mercado e oportunidades de crescimento, condições regulatórias, posição competitiva e o interesse de outras empresas em estratégias de negócios semelhantes, tendências tecnológicas e de mercado, condição financeira futura, e desempenho e impactos financeiros esperados da Transação proposta descritos neste documento. As declarações de previsão deste comunicado de imprensa envolvem riscos e suposições substanciais que podem fazer com que os resultados reais sejam substancialmente diferentes dos resultados expressos ou implícitos em tais declarações. Os riscos e incertezas aplicáveis incluem, entre outros, o risco de que a Transação proposta aqui descrita possa não ser concluída em tempo hábil ou de forma alguma; falha em alcançar os benefícios antecipados da Transação e a estratégia de tesouro de ativos digitais proposta; mudanças nos negócios, mercado, condições financeiras, políticas e regulatórias; riscos relacionados às operações e negócios da Empresa, incluindo a natureza altamente volátil do preço do RAIN e outras criptomoedas; o risco de que o preço das ações ordinárias da Empresa possa estar altamente correlacionado ao preço dos ativos digitais que detém; riscos relacionados ao aumento da concorrência nos setores nos quais a Empresa opera e operará; riscos relacionados a incertezas legais, comerciais, regulatórias e técnicas significativas em relação aos ativos digitais em geral; riscos relacionados ao tratamento dos ativos cripto para fins fiscais nos EUA e no exterior, bem como os riscos e incertezas identificados nos registros da Empresa na Comissão de Valores Mobiliários. As declarações de previsão deste comunicado de imprensa são válidas apenas a partir da data deste documento, e a Empresa não se compromete a atualizar ou alterar nenhuma dessas declarações, exceto conforme exigido pela lei aplicável.

CONTATO ENLIVEX

Shachar Shlosberger, CFO
Enlivex Therapeutics, Ltd.
[email protected]

CONTATO DE RELAÇÕES COM INVESTIDORES

KCSA Strategic Communications
Jack Perkins
[email protected]


GLOBENEWSWIRE (Distribution ID 9592217)

Datavault AI Turns Raw Earth into Digital Power in $7 Million Deal with MTB Mining Ltd.

PHILADELPHIA, Nov. 24, 2025 (GLOBE NEWSWIRE) — via IBN – Datavault AI (“Datavault AI” or the “Company”) (NASDAQ: DVLT), a provider of data monetization, credentialing, digital engagement, and real‑world asset digitization technologies, today announced a $7 million minting deal and a 30% perpetual royalty partnership with Tanzania–based MTB Mining Limited (MTB), setting the stage for what Datavault AI believes is the first major step forward in modernizing how mineral resources are verified, documented, and brought into global commerce with a unified transaction ledger. The deal redefines a commodity by digitizing Real World Assets (RWA) for monetization. Under Datavault AI’s patented Sumerian® technology, rare earth minerals are being transformed into verified, traceable, digitized assets to be traded on the forthcoming International Elements Exchange™.

This agreement with MTB delivers a blueprint for how physical assets evolve into digital assets.

Africa Steps into the Global Ledger

For generations, Africa supplied the raw materials that were integral in building modern industry. Today, MTB, headquartered in Tanzania, controls over 25 million metric tons of copper reserves and 2.44 square kilometers of proven mineral reserves. Through its alliance with Datavault AI, MTB’s resources are entering the global marketplace in digital form. Each unit of copper, gold, tin, or diamond will carry verified proof of origin, ownership, and value.

The partnership includes the Windsor Ruby, a gemstone that drew global attention when it was discovered near the village of Winza in 2007. Renowned for its deep crimson hue and near–perfect clarity, it rivaled the finest Burmese rubies and quickly drew attention from major luxury houses including Van Cleef & Arpels. Through Datavault AI’s Sumerian® Anchors, the Windsor Ruby will carry a permanent digital signature that is immutable and verifiable. Not only can Sumerian® Anchors provide verification for famous gemstones like the Windsor Ruby, the verification technology can be applied to any precious gemstone.

For Tanzania, where mining represents a vast amount of export value, digitally verifiable asset records represent more than a technological milestone; it is economic modernization. It opens the door for lending, collateralization, and cross–border trade using verified digital assets.

The Proof Economy Arrives

“This deal is a milestone for technology and transparency. By minting real world assets, we are creating compliant, transparent pathways to monetize natural wealth on a global scale,” said Nathaniel Bradley, Datavault AI Chief Executive Officer and co–founder.

Bradley’s message reflects Datavault AI’s broader mission: the Company is building the infrastructure for a data–driven economy where value is established by verification and trusted information.

While the numbers are compelling – a $7 million license fee – the innovative digital architecture provides the promise for future, similar transactions. The International Elements Exchange will operate as a virtual refinery, turning physical assets into digital evidence that can be traded, audited, and monetized.

About Datavault AI

Datavault AI™ (Nasdaq: DVLT) is leading the way in AI driven data experiences, valuation and monetization of assets in the Web 3.0 environment. The Company’s cloud–based platform provides comprehensive solutions with a collaborative focus in its Acoustic Science and Data Science Divisions. Datavault AI's Acoustic Science Division features WiSA®, ADIO® and Sumerian® patented technologies and industry–first foundational spatial and multichannel wireless HD sound transmission technologies with IP covering audio timing, synchronization and multi–channel interference cancellation. The Data Science Division leverages the power of Web 3.0 and high–performance computing to provide solutions for experiential data perception, valuation and secure monetization. Datavault AI's cloud–based platform provides comprehensive solutions serving multiple industries, including HPC software licensing for sports & entertainment, events & venues, biotech, education, fintech, real estate, healthcare, energy and more. The Information Data Exchange® (IDE) enables Digital Twins, licensing of name, image and likeness (NIL) by securely attaching physical real–world objects to immutable metadata objects, fostering responsible AI with integrity. Datavault AI’s technology suite is completely customizable and offers AI and Machine Learning (ML) automation, third–party integration, detailed analytics and data, marketing automation and advertising monitoring. The Company is headquartered in Philadelphia, PA. Learn more about Datavault AI at www.dvlt.ai.

Forward–Looking Statements

This press release contains “forward–looking statements” (within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, and other securities laws) about Datavault AI and its industry that involve risks and uncertainties. In some cases, you can identify forward–looking statements because they contain words, such as “may,” “might,” “will,” “shall,” “should,” “expects,” “plans,” “anticipates,” “could,” “intends,” “target,” “projects,” “contemplates,” “believes,” “estimates,” “predicts,” “potential,” “goal,” “objective,” “seeks,” “likely” or “continue” or the negative of these words or other similar terms or expressions that concern the Company’s expectations, strategy, plans or intentions. The absence of these words does not mean that a statement is not forward–looking. Such forward–looking statements, including, but not limited to, statements regarding future events, Datavault AI’s partnership with MTB, including the potential royalty opportunities, the ability of tokenization of minerals and the potential for use in lending, collateralization and cross–border trade, Datavault AI’s business strategies, long–term objectives, and commercialization plans, the current and prospective technologies, planned developments and potential approvals, as well as the potential for market acceptance and related market opportunities, and other statements that are not historical facts. These statements are based on management’s current expectations and are not predictions of actual performance. These forward–looking statements are provided for illustrative purposes only and are not intended to serve as, and must not be relied on, by any investor as a guarantee, an assurance, a prediction, or a definitive statement of fact or probability. Actual events and circumstances are difficult or impossible to predict and will differ from assumptions. Many actual events and circumstances are beyond the control of Datavault AI. These statements are subject to a number of risks and uncertainties regarding Datavault AI’s business, and actual results may differ materially. These risks and uncertainties include, but are not limited to, general economic, political, and business conditions; the ability of Datavault AI to achieve the benefits of the transactions contemplated pursuant to its partnership with MTB, including receipt of any royalty payments from MTB; the ability of Datavault AI to leverage the MTB transaction as a blueprint for digitizing minerals; the ability of Datavault AI to expand tokenization of minerals into the areas of lending, collateralization and cross–border trade; the ability of Datavault AI to develop and successfully market technologies; the ability of Datavault AI to grow and manage growth profitably and retain its key employees; the risk that the potential technologies that Datavault AI develops may not progress or receive required approvals within expected timelines or at all; risks relating to uncertainty regarding regulatory pathways; the risk that Datavault AI has overestimated the size of the target market, willingness to adopt new technologies, or partnerships; risks that prior results may not be replicated; regulatory and intellectual property risks; and other risks and uncertainties as more fully described in Datavault AI’s filings with the U.S. Securities and Exchange Commission (the “SEC”), including its Annual Report on Form 10–K for the year ended December 31, 2024 and other filings that Datavault AI makes from time to time with the SEC, which are available on the SEC’s website at www.sec.gov, and could cause actual results to vary from expectations. There may be additional risks that Datavault AI presently does not know or that Datavault AI currently believes are immaterial that could also cause actual results to differ from those contained in the forward–looking statements. In addition, forward–looking statements reflect Datavault AI’s expectations, plans, or forecasts of future events and views as of the date of this communication. Datavault AI anticipates that subsequent events and developments will cause such assessments to change. However, while Datavault AI may elect to update these forward–looking statements at some point in the future, Datavault AI specifically disclaims any obligation to do so. These forward–looking statements should not be relied upon as representing Datavault AI’s assessments as of any date subsequent to the date of this communication. Accordingly, investors are cautioned not to place undue reliance on these forward–looking statements.

Corporate Communications
IBN
Austin, Texas
www.InvestorBrandNetwork.com
512.354.7000 Office
[email protected]

Media Inquiries:
[email protected]


GLOBENEWSWIRE (Distribution ID 9591134)

Enlivex Announces $212,000,000 Private Placement to Initiate World’s First Prediction Markets Digital Asset Treasury Strategy, via RAIN token Accumulation, and the Appointment of Matteo Renzi, Former Prime Minister of Italy, to its Board

– Upon the closing of the private placement, Enlivex will adopt the world’s first RAIN prediction markets token digital asset treasury strategy, via RAIN token accumulation.

– RAIN is a fully decentralized predictions and options protocol that redefines predictive market ecosystems and provides a powerful platform for on–chain market creation – built for transparency, automation, and community participation.

– Mr. Matteo Renzi, former Prime Minister of Italy, will be appointed to the Enlivex Board of Directors following closing of the private placement.

– Enlivex to continue clinical development of Allocetra™, a potentially game–changing knee osteoarthritis therapeutic, a growing market with significant unmet medical need.

– Price per share of $1.00, representing a premium of 11.5% from previous closing price.

NES–ZIONA, Israel, Nov. 24, 2025 (GLOBE NEWSWIRE) — Enlivex Therapeutics Ltd. (Nasdaq: ENLV, “Enlivex” or “the Company”), a clinical–stage macrophage reprogramming immunotherapy company, today announced that it has entered into a securities purchase agreement for a private investment in public equity (PIPE) for the purchase and sale of 212,000,000 ordinary shares (or ordinary share equivalents in lieu thereof) at a price of $1.00 per share, representing a premium of 11.5% from the closing price of the stock on November 21, 2025, for expected aggregate gross proceeds of approximately $212,000,000 (funded in a combination of $USD and USDT), before deducting placement agent fees and other offering expenses (the “Transaction”). Enlivex intends to use net proceeds from the PIPE to implement the first RAIN prediction markets token treasury strategy, while continuing its focus on the Company’s core business operations.

RAIN is a fully decentralized predictions and options protocol built on the Arbitrum network. The protocol is fully permissionless, allowing anyone to create and trade custom options on any market. Market outcomes can be AI–resolved, and the platform is governed by the RAIN token, which features a built–in, deflationary Buyback & Burn mechanism. Designed to be the “Uniswap” of prediction markets, RAIN is a protocol where anyone, from anywhere, can create any type of market, whether it's public or private, in any language.

“With the recent institutional interest in leading prediction markets companies – $2 billion investment by NYSE’s parent company in Polymarket, and Kalshi’s $300 million financing round led by Andreessen Horowitz (a16z) and Sequoia Capital – it appears that this industry is maturing and has strong growth potential. We believe that following the closing of this transaction and the implementation of the RAIN treasury strategy, Enlivex will become the first U.S.–traded public company to provide investors with an exposure to prediction markets, one of the fastest growing sectors in the crypto industry”, stated Shai Novik, Chairman of the Board of Directors of Enlivex. “RAIN’s decentralized protocol uses blockchain technology to let participants trade on expectations of future events, and we believe it will become a dominant force in this expanding market segment.”

Mr. Novik added, “Alongside managing the RAIN treasury portfolio, Enlivex will continue its existing operations focused on late–stage clinical development of Allocetra™, a novel therapy designed to treat the joint disease osteoarthritis. Osteoarthritis is by far the most common form of arthritis, affecting more than 32.5 million Americans and more than 300 million individuals worldwide. I would like to welcome Mr. Matteo Renzi to the Board of Directors of Enlivex and am looking forward to working together with Mr. Renzi to build shareholder value for Enlivex shareholders.”

The closing of the Transaction is expected to occur on or before November 25, 2025 (the “Closing”), subject to the satisfaction of customary closing conditions.

BTIG is serving as the sole placement agent and exclusive financial advisor for the Transaction. Greenberg Traurig, P.A. and FISCHER (FBC & Co.) serve as legal counsels to Enlivex, and DLA Piper and Gornitzky & Co. serve as legal counsels to BTIG.

This press release shall not constitute an offer to sell, or the solicitation of an offer to buy, any securities and shall not constitute an offer, solicitation or sale in any jurisdiction in which such offer, solicitation or sale would be unlawful.

ABOUT ENLIVEX

Enlivex will be the first publicly–listed company to develop a treasury strategy centered on RAIN, which will serve as the primary treasury reserve asset of the Company. In adopting its new treasury policy, Enlivex intends to provide investors with exposure to RAIN and to advocate for its role as digital capital.

In addition, Enlivex has an operating business focused on late–stage clinical development of Allocetra™, a novel therapy designed to treat the joint disease osteoarthritis. Osteoarthritis is by far the most common form of arthritis, affecting more than 32.5 million Americans and more than 300 million individuals worldwide. About half of knees with ACL injuries develop osteoarthritis within 5 to 15 years. 78 million Americans are projected to have osteoarthritis by the year 2040. Symptomatic knee osteoarthritis is particularly prevalent and disabling, with 40% of men and 47% of women developing knee osteoarthritis in their lifetimes. Osteoarthritis accounts for over one million hospitalizations annually in the United States, primarily for total joint replacement. The burden of osteoarthritis is enormous, and the need for treatments that reduce pain and attendant disability for persons with osteoarthritis is critical. To the Company’s knowledge, there are currently no medications approved by either the U.S. Food and Drug Administration (FDA) or the European Medicines Agency (EMA) that have been demonstrated to arrest, slow or reverse progression of structural damage in the joint.

Forward–Looking Statements

This press release contains forward–looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These forward–looking statements may be identified by words such as “expects,” “plans,” “projects,” “will,” “may,” “anticipates,” “believes,” “should,” “would,” “could,” “intends,” “estimates,” “suggests,” “target,” “has the potential to” and other words of similar meaning, including statements relating to the anticipated benefits and timing of the completion of the proposed Transaction and related transactions, the intended use of proceeds from the Transaction, the assets to be held by the Company, the expected future market, price and liquidity of the digital assets the Company acquires, the macro and political conditions surrounding digital assets, the Company’s plan for value creation and strategic advantages, market size and growth opportunities, regulatory conditions, competitive position and the interest of other corporations in similar business strategies, technological and market trends, future financial condition and performance and the expected financial impacts of the proposed Transaction described herein. Each forward–looking statement contained in this press release is subject to risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statement. Applicable risks and uncertainties include, among others, the risk that the proposed Transaction described herein may not be completed in a timely manner or at all; failure to realize the anticipated benefits of the Transaction and the proposed digital asset treasury strategy; changes in business, market, financial, political and regulatory conditions; risks relating to the Company’s operations and business, including the highly volatile nature of the price of RAIN and other cryptocurrencies; the risk that the price of the Company’s ordinary shares may be highly correlated to the price of the digital assets that it holds; risks related to increased competition in the industries in which the Company does and will operate; risks relating to significant legal, commercial, regulatory and technical uncertainty regarding digital assets generally; risks relating to the treatment of crypto assets for U.S. and foreign tax purposes, as well as those risks and uncertainties identified in the Company’s filings with the Securities and Exchange Commission. The forward–looking statements in this press release speak only as of the date of this document, and the Company undertakes no obligation to update or revise any of these statements, except as required by applicable law.

ENLIVEX CONTACT

Shachar Shlosberger, CFO
Enlivex Therapeutics, Ltd.
[email protected]

INVESTOR RELATIONS CONTACT

KCSA Strategic Communications
Jack Perkins
[email protected]


GLOBENEWSWIRE (Distribution ID 9591212)

Namib Minerals Provides Business Update

How Mine Expansion to 55,000 Tonnes Per Month Targeting H2 2026 Operational Date
Enabling Works Commenced at Redwing; 8–Month Dewatering Program to Begin
Company Outlines $300–400 Million Capital Plan with Non–Dilutive Funding Strategy
Management to Host Business Update Conference Call at 8:00 a.m. Eastern Time

NEW YORK, Nov. 24, 2025 (GLOBE NEWSWIRE) — Namib Minerals (“Namib Minerals” or “the Company”), (Nasdaq: NAMM), an established African gold producer with a portfolio of mining and exploration assets in Zimbabwe today provided a business update on its strategic growth initiatives.

“As a publicly traded company, we are committed to transparent communication as we advance our growth strategy,” said Ibrahima Sory Tall, Chief Executive Officer of Namib Minerals. “We are focused on building Namib Minerals into a multi–asset, mid–tier producer through operational optimization at How Mine and the disciplined restart of our Mazowe and Redwing mines. Our engagement of WSP for comprehensive feasibility studies, combined with the commencement of enabling works at Redwing and capacity expansion initiatives at How Mine, demonstrates tangible progress toward our vision. We look forward to updating the investment community on our strategic roadmap and near–term milestones.”

Strategic Growth Update
Since listing on the Nasdaq Stock Exchange in June 2025, Namib Minerals has executed on its strategy to transform from a single–mine operator into a multi–asset gold producer. The Company is advancing a three–pillar growth strategy: operational excellence at How Mine, strategic restarts of Mazowe and Redwing mines, and portfolio diversification through critical minerals exploration.

How Mine Capacity Expansion
As part of its commitment to operational improvement at How Mine, the Company is advancing plans to expand ore milling capacity from 40,500 tonnes per month in 2024 to 55,000 tonnes per month, representing an approximately 36% increase in throughput capacity. The Company is currently working on the procurement of the required equipment and expects this expansion to be operational during the second half of 2026. This capacity expansion will enable the Company to process higher ore volumes and offset the reduction in grade experienced to date in 2025.

Restart Enabling Works
At Redwing, the Company has commenced enabling works. Dewatering is scheduled to commence during the feasibility study phase and is expected to take approximately eight months to reach the targeted mining levels. Dewatering is a critical first step in the restart sequence, allowing the Company to assess underground conditions, refurbish infrastructure, and prepare for a phased production ramp–up. Concurrently, surface–infrastructure and power–supply upgrades will be planned to align with the restart timeline.

At Mazowe, the Company is advancing surface infrastructure work, including power, water, and tailings management systems, alongside detailed engineering studies to optimize the restart sequence and capital efficiency.

WSP Feasibility Studies
Supporting this disciplined approach, the Company has engaged WSP to conduct comprehensive feasibility studies for both Redwing and Mazowe. As announced on November 10, 2025, WSP has been appointed to execute S–K 1300 compliant feasibility studies for both mines simultaneously. Both mines are currently under care and maintenance and require completion of dewatering and resource drilling before redevelopment can commence. The program is expected to be completed over 12 to 18 months and will provide the technical foundation for reserve conversion, permitting, and financing discussions.

Long–Term Strategic Objective
The Company's vision is to build Namib Minerals into a multi–asset, mid–tier gold producer, working toward a strategic goal of ultimately producing 300,000 ounces per year. This represents a long–term corporate objective, not production guidance or a forecast, and is not based on a Preliminary Economic Assessment, Pre–Feasibility Study, or Feasibility Study. Achievement of this objective is contingent upon execution of the Company's long–term strategy, including the successful execution of restart programs and expansion of mines and other exploration and development goals. 

Preliminary Capital Requirements
The Company's preliminary estimate is that the total funding requirement for the expansion program is expected to fall within a range of $300 million to $400 million, with the majority allocated to Redwing Mine. The Company is pursuing a balanced funding mix including structured solutions that minimize dilution and prioritize project debt, strategic partnerships, and internally–generated cash flows to minimize shareholder dilution while supporting growth initiatives. The Company is in dialogue with multiple capital providers to support its growth plans. The Company’s estimated funding requirement amount is preliminary and subject to completion of feasibility studies, final engineering outcomes, market conditions, and equipment costs and other risks and uncertainties, many of which are beyond the Company's control.

Conference Call Information
Interested investors and other parties can listen to a webcast of the live conference call by logging onto the Investor Relations section of the Company's website at https://namibminerals.gcs–web.com/. An archived replay of the webcast will be available on the Company’s website shortly after the event concludes.

Participants may also access the call by dialing (877) 407–9039 for domestic callers or (201) 689–8470 for international callers.

Namib Minerals management will incorporate responses to a selection of shareholders’ frequently asked questions during the webcast. Shareholders are invited to submit questions via the investor relations email address: [email protected]. Please include the hashtag #askNamib in the subject line.

About Namib Minerals
Namib Minerals (NASDAQ: NAMM) is a gold producer, developer and explorer with operations focused in Zimbabwe. Namib Minerals is a significant player in Africa’s mining industry, driving sustainable growth and innovation across the sector. Currently Namib Minerals operates the How Mine, an underground gold mine in Zimbabwe, and aims to restart two assets in Zimbabwe. For additional information, please visit namibminerals.com.

Forward–Looking Statements

This press release includes forward–looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. All statements other than statements of historical facts contained in this update are forward–looking statements. Any statements that refer to estimates or other characterizations of future events or circumstances, including any underlying assumptions, are also forward–looking statements. Forward–looking statements include, without limitation, our management teams’ expectations of funding frameworks and anticipated timelines and costs of the restart of the Mazowe and Redwing Mines, and related assumptions. The forward–looking statements are based on our current expectations and are inherently subject to uncertainties and changes in circumstance and their potential effects and speak only as of the date of such statement. There can be no assurance that future developments will be those that have been anticipated. These forward–looking statements involve a number of risks and uncertainties which include, but are not limited to, (i) market risks, including the price of gold and equipment; (ii) the risk that the Company may not be able to successfully develop its assets as planned, including expanding the How mine and restarting and expanding the Redwing and Mazowe Mines; (iii) the risk that Namib Minerals will be unable to raise additional capital to execute its business plan, which may not be available on acceptable terms or at all; and (iv) political and social risks of operating in Zimbabwe and the DRC. The foregoing list is not exhaustive. You should carefully consider the foregoing factors, any other factors discussed in this press release and the other risks and uncertainties described in the filings we make with Securities and Exchange Commission (the “SEC”). We caution you against placing undue reliance on forward–looking statements, which reflect current beliefs and are based on information currently available as of the date a forward–looking statement is made.

Contacts:
Namib Minerals:
Ibrahima Sory Tall
CEO & Director
Investor Relations:
[email protected]


GLOBENEWSWIRE (Distribution ID 9591191)

Namib Minerals Schedules Business Update Call

NEW YORK, Nov. 20, 2025 (GLOBE NEWSWIRE) — Namib Minerals (“Namib Minerals” or “the Company”), (Nasdaq: NAMM), an established African gold producer with a portfolio of mining and exploration assets in Zimbabwe and the Democratic Republic of Congo, today announced that management will host a webcast and conference call to provide a business update at 8:00 AM ET on Monday, November 24, 2025.

Interested investors and other parties can listen to a webcast of the live conference call by logging onto the Investor Relations section of the Company's website at https://namibminerals.gcs–web.com/. An archived replay of the webcast will be available shortly after the event concludes.

Participants may also access the call by dialing (877) 407–9039 for domestic callers or (201) 689–8470 for international callers.

Namib Minerals management will incorporate responses to a selection of shareholders’ frequently asked questions during the webcast. Shareholders are invited to submit questions via the investor relations email address: [email protected]. Please include the hashtag #askNamib in the subject line.

About Namib Minerals

Namib Minerals (NASDAQ: NAMM) is a gold producer, developer and explorer with operations focused in Zimbabwe. Namib Minerals is a significant player in Africa’s mining industry, driving sustainable growth and innovation across the sector. Currently Namib Minerals operates the How Mine, an underground gold mine in Zimbabwe, and aims to restart two assets in Zimbabwe, with additional exploration assets in the DRC. For additional information, please visit namibminerals.com.

Contacts:
Namib Minerals:
Ibrahima Sory Tall
CEO & Director
Investor Relations:
[email protected]


GLOBENEWSWIRE (Distribution ID 9580064)

Information on the total number of voting rights and shares

REGULATED INFORMATION

Information on the total number of voting rights and shares

Mont–Saint–Guibert (Belgium), November 20, 2025, 10:30 pm CET / 4:30 pm ET – In accordance with article  15 of the Law of 2 May 2007 on the disclosure of large shareholdings, Nyxoah SA (Euronext Brussels and Nasdaq: NYXH) publishes the below information following the issue of new shares.

  • Share capital: EUR 6.504.688,76
  • Total number of securities carrying voting rights: 43,026,460 (all ordinary shares)
  • Total number of voting rights (= denominator): 43,026,460 (all relating to ordinary shares)
  • Number of rights to subscribe to securities carrying voting rights not yet issued: 3,258,819 (all granted subscription rights; this number excludes 692,677 subscription rights that were issued but not yet granted)

*

* *

Contact:
Nyxoah
John Landry, CFO
[email protected]

Attachment


GLOBENEWSWIRE (Distribution ID 1001140138)